PACLITAXEL IN BREAST CANCER Paclitaxel is a novel cytotoxic agent that binds to the beta-tubulinmonomer, inducing permanent microtubular polymerization. [24,25] The resultingloss of . Paclitaxel has emerged as an important agent in the treatment of breast cancer. The efficacy and tolerability of this agent, as well as its lack of cross-resistance with anthracyclines, have spurred Cited by:
Paclitaxel is used to treat people with primary breast cancer (cancer that has not spread beyond the breast or the lymph nodes under the arm) in combination with other drugs. It might also be given as part of a clinical trial for primary .